Presenilin-Based Genetic Screens in Drosophila melanogaster Identify Novel Notch Pathway Modifiers

Presenilin is the enzymatic component of γ-secretase, a multisubunit intramembrane protease that processes several transmembrane receptors, such as the amyloid precursor protein (APP). Mutations in human Presenilins lead to altered APP cleavage and early-onset Alzheimer's disease. Presenilins a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Mahoney, Matt B., Parks, Annette L., Ruddy, David A., Tiong, Stanley Y. K., Esengil, Hanife, Phan, Alexander C., Philandrinos, Panos, Winter, Christopher G., Chatterjee, Runa, Huppert, Kari, Fisher, William W., L'Archeveque, Lynn, Mapa, Felipa A., Woo, Wendy, Ellis, Michael C., Curtis, Daniel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Copyright © 2006 by the Genetics Society of America 2006
Aiheet:
Investigations
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456381/
https://ncbi.nlm.nih.gov/pubmed/16415372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.035170
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia