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Efficient Gene Targeting in Drosophila With Zinc-Finger Nucleases
This report describes high-frequency germline gene targeting at two genomic loci in Drosophila melanogaster, y and ry. In the best case, nearly all induced parents produced mutant progeny; 25% of their offspring were new mutants and most of these were targeted gene replacements resulting from homolo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Copyright © 2006 by the Genetics Society of America
2006
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456366/ https://ncbi.nlm.nih.gov/pubmed/16452139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.052829 |
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