A role of the kinase mTOR in cellular transformation induced by the oncoproteins P3k and Akt

The oncoproteins P3k (homolog of the catalytic subunit of class IA phosphoinositide 3-kinase) and Akt (protein kinase B) induce oncogenic transformation of chicken embryo fibroblasts. The transformed cells show constitutive phosphorylation of the positive regulator of translation p70S6 kinase (S6K)...

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Detaylı Bibliyografya
Asıl Yazarlar: Aoki, Masahiro, Blazek, Erik, Vogt, Peter K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2001
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC14557/
https://ncbi.nlm.nih.gov/pubmed/11134523
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