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Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA
We have determined the 3.0 Å resolution structure of wild-type HIV-1 reverse transcriptase in complex with an RNA:DNA oligonucleotide whose sequence includes a purine-rich segment from the HIV-1 genome called the polypurine tract (PPT). The PPT is resistant to ribonuclease H (RNase H) cleavage and i...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2001
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC145536/ https://ncbi.nlm.nih.gov/pubmed/11250910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.6.1449 |
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