Mad2 phosphorylation regulates its association with Mad1 and the APC/C

Improper attachment of the mitotic spindle to the kinetochores of paired sister chromatids in mitosis is monitored by a checkpoint that leads to an arrest in early metaphase. This arrest requires the inhibitory association of Mad2 with the anaphase promoting complex/cyclosome (APC/C). It is not know...

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Pubblicato in:	EMBO J
Autori principali:	Wassmann, Katja, Liberal, Vasco, Benezra, Robert
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2003
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145433/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12574116/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg071
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