MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity
Cell cycle progression is monitored by checkpoint mechanisms that ensure faithful duplication and accurate segregation of the genome. Defects in spindle assembly or spindle-kinetochore attachment activate the mitotic checkpoint. Once activated, this checkpoint arrests cells prior to the metaphase-an...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24983/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9356466/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.23.12431 |
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