p55CDC25 is a nuclear protein required for the initiation of mitosis in human cells.

The cdc25+ gene of fission yeast encodes a phosphotyrosine phosphatase that dephosphorylates tyrosine-15 of p34cdc2 and thereby activates p34cdc2/cyclin to bring about entry into M phase. We have recently cloned a human homolog, CDC25, which rescues the M-phase initiation defect of yeast cdc25 tempe...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Millar, J B, Blevitt, J, Gerace, L, Sadhu, K, Featherstone, C, Russell, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52956/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1961714/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.23.10500
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