p55CDC25 is a nuclear protein required for the initiation of mitosis in human cells.
The cdc25+ gene of fission yeast encodes a phosphotyrosine phosphatase that dephosphorylates tyrosine-15 of p34cdc2 and thereby activates p34cdc2/cyclin to bring about entry into M phase. We have recently cloned a human homolog, CDC25, which rescues the M-phase initiation defect of yeast cdc25 tempe...
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| Опубліковано в:: | Proc Natl Acad Sci U S A |
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| Автори: | , , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
National Academy of Sciences
1991
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52956/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1961714/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.23.10500 |
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