Mad2 phosphorylation regulates its association with Mad1 and the APC/C
Improper attachment of the mitotic spindle to the kinetochores of paired sister chromatids in mitosis is monitored by a checkpoint that leads to an arrest in early metaphase. This arrest requires the inhibitory association of Mad2 with the anaphase promoting complex/cyclosome (APC/C). It is not know...
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| Gepubliceerd in: | EMBO J |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2003
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145433/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12574116/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg071 |
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