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Genomic analysis of insertion behavior and target specificity of mini-Tn7 and Tn3 transposons in Saccharomyces cerevisiae

Transposons are widely employed as tools for gene disruption. Ideally, they should display unbiased insertion behavior, and incorporate readily into any genomic DNA to which they are exposed. However, many transposons preferentially insert at specific nucleotide sequences. It is unclear to what exte...

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Bibliographic Details
Main Authors: Seringhaus, Michael, Kumar, Anuj, Hartigan, John, Snyder, Michael, Gerstein, Mark
Format: Artigo
Language:Inglês
Published: Oxford University Press 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450332/
https://ncbi.nlm.nih.gov/pubmed/16648358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl184
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