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Genomic analysis of insertion behavior and target specificity of mini-Tn7 and Tn3 transposons in Saccharomyces cerevisiae

Transposons are widely employed as tools for gene disruption. Ideally, they should display unbiased insertion behavior, and incorporate readily into any genomic DNA to which they are exposed. However, many transposons preferentially insert at specific nucleotide sequences. It is unclear to what exte...

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Bibliografiske detaljer
Main Authors: Seringhaus, Michael, Kumar, Anuj, Hartigan, John, Snyder, Michael, Gerstein, Mark
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450332/
https://ncbi.nlm.nih.gov/pubmed/16648358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl184
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