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Electron trap for DNA-bound repair enzymes: A strategy for DNA-mediated signaling
Despite a low copy number within the cell, base excision repair (BER) enzymes readily detect DNA base lesions and mismatches. These enzymes also contain [Fe(4)S(4)] clusters, yet a redox role for these iron cofactors had been unclear. Here, we provide evidence that BER proteins may use DNA-mediated...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1450131/ https://ncbi.nlm.nih.gov/pubmed/16505354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600239103 |
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