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Modulation of Replication Protein A Function by Its Hyperphosphorylation-induced Conformational Change Involving DNA Binding Domain B

Human replication protein A (RPA), composed of RPA70, RPA32, and RPA14 subunits, undergoes hyperphosphorylation in cells in response to DNA damage. Hyperphosphorylation that occurs predominately in the N-terminal region of RPA32 is believed to play a role in modulating the cellular activities of RPA...

詳細記述

保存先:
書誌詳細
主要な著者: Liu, Yiyong, Kvaratskhelia, Mamuka, Hess, Sonja, Qu, Youxing, Zou, Yue
フォーマット: Artigo
言語:Inglês
出版事項: 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450107/
https://ncbi.nlm.nih.gov/pubmed/16006651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M505705200
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