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Preferential localization of hyperphosphorylated replication protein A to double-strand break repair and checkpoint complexes upon DNA damage

RPA (replication protein A) is an essential factor for DNA DSB (double-strand break) repair and cell cycle checkpoint activation. The 32 kDa subunit of RPA undergoes hyperphosphorylation in response to cellular genotoxic insults. However, the potential involvement of hyperphosphorylated RPA in DSB r...

詳細記述

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書誌詳細
主要な著者: Wu, Xiaoming, Yang, Zhengguan, Liu, Yiyong, Zou, Yue
フォーマット: Artigo
言語:Inglês
出版事項: Portland Press Ltd. 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276948/
https://ncbi.nlm.nih.gov/pubmed/15929725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050379
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