Preferential localization of hyperphosphorylated replication protein A to double-strand break repair and checkpoint complexes upon DNA damage

RPA (replication protein A) is an essential factor for DNA DSB (double-strand break) repair and cell cycle checkpoint activation. The 32 kDa subunit of RPA undergoes hyperphosphorylation in response to cellular genotoxic insults. However, the potential involvement of hyperphosphorylated RPA in DSB r...

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Hlavní autoři: Wu, Xiaoming, Yang, Zhengguan, Liu, Yiyong, Zou, Yue
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2005
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276948/
https://ncbi.nlm.nih.gov/pubmed/15929725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050379
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