Effects of DNA Adduct Structure and Sequence Context on Strand Opening of Repair Intermediates and Incision by UvrABC Nuclease

DNA damage recognition of nucleotide excision repair (NER) in Escherichia coli is achieved by at least two steps. In the first step, a helical distortion is recognized, which leads to a strand opening at the lesion site. The second step involves the recognition of the type of chemical modification i...

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Bibliographic Details
Main Authors: Zou, Yue, Shell, Steven M., Luo, Charlie, Yang, Zhengguan, Utzat, Christopher D., Basu, Ashis K., Geacintov, Nicholas E.
Format: Artigo
Language:Inglês
Published: 2003
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450104/
https://ncbi.nlm.nih.gov/pubmed/14580212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi034446e
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