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Effects of DNA Adduct Structure and Sequence Context on Strand Opening of Repair Intermediates and Incision by UvrABC Nuclease

DNA damage recognition of nucleotide excision repair (NER) in Escherichia coli is achieved by at least two steps. In the first step, a helical distortion is recognized, which leads to a strand opening at the lesion site. The second step involves the recognition of the type of chemical modification i...

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Bibliografiske detaljer
Main Authors: Zou, Yue, Shell, Steven M., Luo, Charlie, Yang, Zhengguan, Utzat, Christopher D., Basu, Ashis K., Geacintov, Nicholas E.
Format: Artigo
Sprog:Inglês
Udgivet: 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450104/
https://ncbi.nlm.nih.gov/pubmed/14580212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi034446e
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