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Effects of DNA Adduct Structure and Sequence Context on Strand Opening of Repair Intermediates and Incision by UvrABC Nuclease

DNA damage recognition of nucleotide excision repair (NER) in Escherichia coli is achieved by at least two steps. In the first step, a helical distortion is recognized, which leads to a strand opening at the lesion site. The second step involves the recognition of the type of chemical modification i...

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Библиографические подробности
Главные авторы: Zou, Yue, Shell, Steven M., Luo, Charlie, Yang, Zhengguan, Utzat, Christopher D., Basu, Ashis K., Geacintov, Nicholas E.
Формат: Artigo
Язык:Inglês
Опубликовано: 2003
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450104/
https://ncbi.nlm.nih.gov/pubmed/14580212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi034446e
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