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Recognition and incision of site-specifically modified C8 guanine adducts formed by 2-aminofluorene, N-acetyl-2-aminofluorene and 1-nitropyrene by UvrABC nuclease

Nucleotide excision repair plays a crucial role in removing many types of DNA adducts formed by UV light and chemical carcinogens. We have examined the interactions of Escherichia coli UvrABC nuclease proteins with three site-specific C8 guanine adducts formed by the carcinogens 2-aminofluorene (AF)...

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Détails bibliographiques
Auteurs principaux: Luo, Charlie, Krishnasamy, Ramji, Basu, Ashis K., Zou, Yue
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC110764/
https://ncbi.nlm.nih.gov/pubmed/11000263
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