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Recognition and Incision of γ-Radiation-Induced Cross-Linked Guanine—Thymine Tandem Lesion G[8,5-Me]T by UvrABC Nuclease

Nucleotide excision repair (NER) plays an important role in maintaining the integrity of DNA by removing various types of bulky or distorting DNA adducts in both prokaryotic and eukaryotic cells. In Escherichia coli, the excision repair proteins UvrA, UvrB, and UvrC recognize and incise the bulky DN...

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Bibliografiske detaljer
Udgivet i:Chem Res Toxicol
Main Authors: Yang, Zhengguan, Colis, Laureen C., Basu, Ashis K., Zou, Yue
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392644/
https://ncbi.nlm.nih.gov/pubmed/16167825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx050147+
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