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Recognition and Incision of γ-Radiation-Induced Cross-Linked Guanine—Thymine Tandem Lesion G[8,5-Me]T by UvrABC Nuclease

Nucleotide excision repair (NER) plays an important role in maintaining the integrity of DNA by removing various types of bulky or distorting DNA adducts in both prokaryotic and eukaryotic cells. In Escherichia coli, the excision repair proteins UvrA, UvrB, and UvrC recognize and incise the bulky DN...

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Détails bibliographiques
Publié dans:Chem Res Toxicol
Auteurs principaux: Yang, Zhengguan, Colis, Laureen C., Basu, Ashis K., Zou, Yue
Format: Artigo
Langue:Inglês
Publié: 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392644/
https://ncbi.nlm.nih.gov/pubmed/16167825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx050147+
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