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The allosteric enhancer PD81,723 increases chimaeric A(1)/A(2A) adenosine receptor coupling with G(s)
PD81,723 {(2-amino-4,5-dimethyl-3-thienyl)-[3-(trifluromethyl)-phenyl]methanone} is a selective allosteric enhancer of the G(i)-coupled A(1) AR (adenosine receptor) that is without effect on G(s)-coupled A(2A) ARs. PD81,723 elicits a decrease in the dissociation kinetics of A(1) AR agonist radioliga...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Portland Press Ltd.
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1449996/ https://ncbi.nlm.nih.gov/pubmed/16390330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051422 |
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