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Inhibition of muscarinic K(+) current in guinea-pig atrial myocytes by PD 81,723, an allosteric enhancer of adenosine binding to A(1) receptors

1. PD 81,723 has been shown to enhance binding of adenosine to A(1) receptors by stabilizing G protein-receptor coupling (‘allosteric enhancement'). Evidence has been provided that in the perfused hearts and isolated atria PD 81,723 causes a sensitization to adenosine via this mechanism. 2. We...

詳細記述

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書誌詳細
主要な著者: Brandts, B, Bünemann, M, Hluchy, J, Sabin, G V, Pott, L
フォーマット: Artigo
言語:Inglês
出版事項: 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564805/
https://ncbi.nlm.nih.gov/pubmed/9249260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701254
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