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Inhibition of muscarinic K(+) current in guinea-pig atrial myocytes by PD 81,723, an allosteric enhancer of adenosine binding to A(1) receptors
1. PD 81,723 has been shown to enhance binding of adenosine to A(1) receptors by stabilizing G protein-receptor coupling (‘allosteric enhancement'). Evidence has been provided that in the perfused hearts and isolated atria PD 81,723 causes a sensitization to adenosine via this mechanism. 2. We...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564805/ https://ncbi.nlm.nih.gov/pubmed/9249260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701254 |
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