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The allosteric enhancer PD81,723 increases chimaeric A(1)/A(2A) adenosine receptor coupling with G(s)

PD81,723 {(2-amino-4,5-dimethyl-3-thienyl)-[3-(trifluromethyl)-phenyl]methanone} is a selective allosteric enhancer of the G(i)-coupled A(1) AR (adenosine receptor) that is without effect on G(s)-coupled A(2A) ARs. PD81,723 elicits a decrease in the dissociation kinetics of A(1) AR agonist radioliga...

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Bibliografiske detaljer
Main Authors: Bhattacharya, Samita, Youkey, Rebecca L., Ghartey, Kobina, Leonard, Matthew, Linden, Joel, Tucker, Amy L.
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449996/
https://ncbi.nlm.nih.gov/pubmed/16390330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051422
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