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Predictive modelling of topology and loop variations in dimeric DNA quadruplex structures

We have used a combination of simulated annealing (SA), molecular dynamics (MD) and locally enhanced sampling (LES) methods in order to predict the favourable topologies and loop conformations of dimeric DNA quadruplexes with T2 or T3 loops. This follows on from our previous MD simulation studies on...

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Bibliografski detalji
Glavni autori: Hazel, Pascale, Parkinson, Gary N, Neidle, Stephen
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449907/
https://ncbi.nlm.nih.gov/pubmed/16641317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl182
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