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Pharmacological promotion of inclusion formation: A therapeutic approach for Huntington’s and Parkinson’s diseases

Misfolded proteins accumulate in many neurodegenerative diseases, including huntingtin in Huntington’s disease and α-synuclein in Parkinson’s disease. The disease-causing proteins can take various conformations and are prone to aggregate and form larger cytoplasmic or nuclear inclusions. One approac...

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Bibliografiset tiedot
Päätekijät: Bodner, Ruth A., Outeiro, Tiago Fleming, Altmann, Stephen, Maxwell, Michele M., Cho, Stephanie H., Hyman, Bradley T., McLean, Pamela J., Young, Anne B., Housman, David E., Kazantsev, Aleksey G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2006
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449678/
https://ncbi.nlm.nih.gov/pubmed/16537516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511256103
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