Structural basis of hepatocyte growth factor/scatter factor and MET signalling

The polypeptide growth factor, hepatocyte growth factor/scatter factor (HGF/SF), shares the multidomain structure and proteolytic mechanism of activation of plasminogen and other complex serine proteinases. HGF/SF, however, has no enzymatic activity. Instead, it controls the growth, morphogenesis, o...

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Autors principals: Gherardi, Ermanno, Sandin, Sara, Petoukhov, Maxim V., Finch, John, Youles, Mark E., Öfverstedt, Lars-Göran, Miguel, Ricardo N., Blundell, Tom L., Vande Woude, George F., Skoglund, Ulf, Svergun, Dmitri I.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449643/
https://ncbi.nlm.nih.gov/pubmed/16537482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509040103
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