Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor

Little is known about the large ectodomain of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor (HGF/SF). Here, we establish by deletion mutagenesis that the HGF/SF and heparin-binding sites of MET are contained within a large N-terminal domain span...

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Detalhes bibliográficos
Main Authors: Gherardi, Ermanno, Youles, Mark E., Miguel, Ricardo N., Blundell, Tom L., Iamele, Luisa, Gough, Julian, Bandyopadhyay, Abhishek, Hartmann, Guido, Butler, P. Jonathan G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC218709/
https://ncbi.nlm.nih.gov/pubmed/14528000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2034936100
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