Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor

Little is known about the large ectodomain of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor (HGF/SF). Here, we establish by deletion mutagenesis that the HGF/SF and heparin-binding sites of MET are contained within a large N-terminal domain span...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Gherardi, Ermanno, Youles, Mark E., Miguel, Ricardo N., Blundell, Tom L., Iamele, Luisa, Gough, Julian, Bandyopadhyay, Abhishek, Hartmann, Guido, Butler, P. Jonathan G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2003
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC218709/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14528000/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2034936100
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