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Evidence for Abundant Slightly Deleterious Polymorphisms in Bacterial Populations

The nearly neutral theory of molecular evolution predicts that slightly deleterious mutations subject to purifying selection are widespread in natural populations, particularly those of large effective population size. To test this hypothesis, the standardized difference between pairwise nucleotide...

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Autore principale: Hughes, Austin L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449124/
https://ncbi.nlm.nih.gov/pubmed/15545641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.036939
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