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Synonymous and Nonsynonymous Polymorphisms versus Divergences in Bacterial Genomes

Comparison of the ratio of nonsynonymous to synonymous polymorphisms within species with the ratio of nonsynonymous to synonymous substitutions between species has been widely used as a supposed indicator of positive Darwinian selection, with the ratio of these 2 ratios being designated as a neutral...

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Main Authors: Hughes, Austin L., Friedman, Robert, Rivailler, Pierre, French, Jeffrey O.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734133/
https://ncbi.nlm.nih.gov/pubmed/18667439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msn166
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