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Resistance to Volatile Anesthetics by Mutations Enhancing Excitatory Neurotransmitter Release in Caenorhabditis elegans

The molecular mechanisms whereby volatile general anesthetics (VAs) disrupt behavior remain undefined. In Caenorhabditis elegans mutations in the gene unc-64, which encodes the presynaptic protein syntaxin 1A, produce large allele-specific differences in VA sensitivity. UNC-64 syntaxin normally func...

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Bibliografische gegevens
Hoofdauteurs: Hawasli, Ammar H., Saifee, Owais, Liu, Christine, Nonet, Michael L., Crowder, C. Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Genetics Society of America 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448830/
https://ncbi.nlm.nih.gov/pubmed/15514057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.030502
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