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Resistance to Volatile Anesthetics by Mutations Enhancing Excitatory Neurotransmitter Release in Caenorhabditis elegans

The molecular mechanisms whereby volatile general anesthetics (VAs) disrupt behavior remain undefined. In Caenorhabditis elegans mutations in the gene unc-64, which encodes the presynaptic protein syntaxin 1A, produce large allele-specific differences in VA sensitivity. UNC-64 syntaxin normally func...

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Detalhes bibliográficos
Main Authors: Hawasli, Ammar H., Saifee, Owais, Liu, Christine, Nonet, Michael L., Crowder, C. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448830/
https://ncbi.nlm.nih.gov/pubmed/15514057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.030502
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