Resistance to Volatile Anesthetics by Mutations Enhancing Excitatory Neurotransmitter Release in Caenorhabditis elegans

The molecular mechanisms whereby volatile general anesthetics (VAs) disrupt behavior remain undefined. In Caenorhabditis elegans mutations in the gene unc-64, which encodes the presynaptic protein syntaxin 1A, produce large allele-specific differences in VA sensitivity. UNC-64 syntaxin normally func...

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Bibliographic Details
Main Authors: Hawasli, Ammar H., Saifee, Owais, Liu, Christine, Nonet, Michael L., Crowder, C. Michael
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2004
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448830/
https://ncbi.nlm.nih.gov/pubmed/15514057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.030502
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