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A Gain-of-function Mutation in Adenylate Cyclase Confers Isoflurane Resistance in C. elegans
BACKGROUND: Volatile general anesthetics inhibit neurotransmitter release by a mechanism not fully understood. Genetic evidence in C. elegans has shown that a major mechanism of action of volatile anesthetics acting at clinical concentrations in this animal is presynaptic inhibition of neurotransmis...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3226976/ https://ncbi.nlm.nih.gov/pubmed/22024713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e318239355d |
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