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An Evolutionarily Conserved Presynaptic Protein Is Required for Isoflurane Sensitivity in C. elegans

BACKGROUND: Volatile general anesthetics inhibit neurotransmitter release by an unknown mechanism. A mutation in the presynaptic SNARE protein syntaxin-1A was previously shown to antagonize the anesthetic isoflurane in C. elegans. The mechanism underlying this antagonism may identify presynaptic ane...

詳細記述

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書誌詳細
主要な著者: Metz, Laura B., Dasgupta, Nupur, Liu, Christine, Hunt, Stephen J., Crowder, C. Michael
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792697/
https://ncbi.nlm.nih.gov/pubmed/18043066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.anes.0000291451.49034.b8
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