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An Evolutionarily Conserved Presynaptic Protein Is Required for Isoflurane Sensitivity in C. elegans
BACKGROUND: Volatile general anesthetics inhibit neurotransmitter release by an unknown mechanism. A mutation in the presynaptic SNARE protein syntaxin-1A was previously shown to antagonize the anesthetic isoflurane in C. elegans. The mechanism underlying this antagonism may identify presynaptic ane...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2792697/ https://ncbi.nlm.nih.gov/pubmed/18043066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.anes.0000291451.49034.b8 |
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