Resistance to Volatile Anesthetics by Mutations Enhancing Excitatory Neurotransmitter Release in Caenorhabditis elegans

The molecular mechanisms whereby volatile general anesthetics (VAs) disrupt behavior remain undefined. In Caenorhabditis elegans mutations in the gene unc-64, which encodes the presynaptic protein syntaxin 1A, produce large allele-specific differences in VA sensitivity. UNC-64 syntaxin normally func...

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Main Authors: Hawasli, Ammar H., Saifee, Owais, Liu, Christine, Nonet, Michael L., Crowder, C. Michael
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2004
主題:
Investigations
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448830/
https://ncbi.nlm.nih.gov/pubmed/15514057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.030502
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