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Drosophila melanogaster Prat, a Purine de Novo Synthesis Gene, Has a Pleiotropic Maternal-Effect Phenotype

In Drosophila melanogaster, two genes, Prat and Prat2, encode the enzyme, amidophosphoribosyltransferase, that performs the first and limiting step in purine de novo synthesis. Only Prat mRNA is present in the female germline and 0- to 2-hr embryos prior to the onset of zygotic transcription. We stu...

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Autors principals: Malmanche, Nicolas, Clark, Denise V.
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448727/
https://ncbi.nlm.nih.gov/pubmed/15611171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.033134
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