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Drosophila melanogaster Prat, a Purine de Novo Synthesis Gene, Has a Pleiotropic Maternal-Effect Phenotype

In Drosophila melanogaster, two genes, Prat and Prat2, encode the enzyme, amidophosphoribosyltransferase, that performs the first and limiting step in purine de novo synthesis. Only Prat mRNA is present in the female germline and 0- to 2-hr embryos prior to the onset of zygotic transcription. We stu...

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Detalhes bibliográficos
Main Authors: Malmanche, Nicolas, Clark, Denise V.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448727/
https://ncbi.nlm.nih.gov/pubmed/15611171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.033134
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