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The Purine Synthesis Gene Prat2 Is Required for Drosophila Metamorphosis, as Revealed by Inverted-Repeat-Mediated RNA Interference
PRAT (phosphoribosylamidotransferase; E.C. 2.4.2.14) catalyzes the first reaction in de novo purine nucleotide biosynthesis. In Drosophila melanogaster, the Prat and Prat2 genes are both highly conserved with PRAT sequences from prokaryotes and eukaryotes. However, Prat2 organization and expression...
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| Format: | Artigo |
| Język: | Inglês |
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Copyright © 2006 by the Genetics Society of America
2006
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456287/ https://ncbi.nlm.nih.gov/pubmed/16322507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.045641 |
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