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The Purine Synthesis Gene Prat2 Is Required for Drosophila Metamorphosis, as Revealed by Inverted-Repeat-Mediated RNA Interference

PRAT (phosphoribosylamidotransferase; E.C. 2.4.2.14) catalyzes the first reaction in de novo purine nucleotide biosynthesis. In Drosophila melanogaster, the Prat and Prat2 genes are both highly conserved with PRAT sequences from prokaryotes and eukaryotes. However, Prat2 organization and expression...

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Hlavní autoři: Ji, Yingbiao, Clark, Denise V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Copyright © 2006 by the Genetics Society of America 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456287/
https://ncbi.nlm.nih.gov/pubmed/16322507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.045641
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