Two Drosophila melanogaster mutations block successive steps of de novo purine synthesis.

Drosophila melanogaster purine auxotrophs ade2(1) and ade3(1) have been characterized biochemically. The ade2(1) strain is deficient in the fourth step of the de novo purine synthetic pathway catalyzed by phosphoribosylglycinamidine synthase (phosphoribosylformylglycinamide amidotransferase). The ad...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Henikoff, S, Nash, D, Hards, R, Bleskan, J, Woolford, J F, Naguib, F, Patterson, D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323636/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3086869/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.11.3919
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