Two Drosophila melanogaster mutations block successive steps of de novo purine synthesis.

Drosophila melanogaster purine auxotrophs ade2(1) and ade3(1) have been characterized biochemically. The ade2(1) strain is deficient in the fourth step of the de novo purine synthetic pathway catalyzed by phosphoribosylglycinamidine synthase (phosphoribosylformylglycinamide amidotransferase). The ad...

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Bibliographic Details
Main Authors: Henikoff, S, Nash, D, Hards, R, Bleskan, J, Woolford, J F, Naguib, F, Patterson, D
Format: Artigo
Language:Inglês
Published: 1986
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC323636/
https://ncbi.nlm.nih.gov/pubmed/3086869
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