Multi-level gene expression profiles affected by thymidylate synthase and 5-fluorouracil in colon cancer

BACKGROUND: Thymidylate synthase (TS) is a critical target for cancer chemotherapy and is one of the most extensively studied biomarkers for fluoropyrimidine-based chemotherapy. In addition to its critical role in enzyme catalysis, TS functions as an RNA binding protein to regulate the expression of...

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Main Authors: Xi, Yaguang, Nakajima, Go, Schmitz, John C, Chu, Edward, Ju, Jingfang
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2006
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448211/
https://ncbi.nlm.nih.gov/pubmed/16584549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-7-68
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