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Regulation of p53 expression by thymidylate synthase

Previous studies showed that thymidylate synthase (TS), as an RNA binding protein, regulates its own synthesis by impairing the translation of TS mRNA. In this report, we present evidence that p53 expression is affected in a similar manner by TS. For these studies, we used a TS-depleted human colon...

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Bibliografiske detaljer
Main Authors: Ju, Jingfang, Pedersen-Lane, Joan, Maley, Frank, Chu, Edward
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22369/
https://ncbi.nlm.nih.gov/pubmed/10097112
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