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Reduction of Orc6 expression sensitizes human colon cancer cells to 5-fluorouracil and cisplatin.

Previous studies from our group have shown that the expression levels of Orc6 were highly elevated in colorectal cancer patient specimens and the induction of Orc6 was associated with 5-fluorouracil (5-FU) treatment. The goal of this study was to investigate the molecular and cellular impact of Orc6...

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Autori principali: Elaine J Gavin, Bo Song, Yuan Wang, Yaguang Xi, Jingfang Ju
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2008-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC2603583?pdf=render
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