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Novel Role for RbAp48 in Tissue-Specific, Estrogen Deficiency-Dependent Apoptosis in the Exocrine Glands

Although tissue-specific apoptosis in the exocrine glands in estrogen-deficient mice may contribute to the development of autoimmune exocrinopathy, the molecular mechanism responsible for tissue-specific apoptosis remains obscure. Here we show that RbAp48 overexpression induces p53-mediated apoptosi...

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Bibliografiske detaljer
Main Authors: Ishimaru, Naozumi, Arakaki, Rieko, Omotehara, Fumie, Yamada, Koichi, Mishima, Kenji, Saito, Ichiro, Hayashi, Yoshio
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1446941/
https://ncbi.nlm.nih.gov/pubmed/16581768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.8.2924-2935.2006
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