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Role of endothelial heparanase in delayed-type hypersensitivity
Heparanase is an endoglycosidase that cleaves heparan sulfate (HS), the main polysaccharide of the basement membrane (BM). HS is responsible for BM integrity and barrier function. Hence, enzymatic degradation of HS in the vascular subendothelial BM is a prerequisite for extravasation of immune cells...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society of Hematology
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1444937/ https://ncbi.nlm.nih.gov/pubmed/16384929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-08-3301 |
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