Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease

BACKGROUND: Accumulating evidence suggests that inflammation plays an important role in the progression of Parkinson's disease (PD). Among many inflammatory factors found in the PD brain, cyclooxygenase (COX), specifically the inducible isoform, COX-2, is believed to be a critical enzyme in the...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Vijitruth, Rattanavijit, Liu, Mei, Choi, Dong-Young, Nguyen, Xuan V, Hunter, Randy L, Bing, Guoying
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2006
विषय:
Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440849/
https://ncbi.nlm.nih.gov/pubmed/16566823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-3-6
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