Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease

BACKGROUND: Accumulating evidence suggests that inflammation plays an important role in the progression of Parkinson's disease (PD). Among many inflammatory factors found in the PD brain, cyclooxygenase (COX), specifically the inducible isoform, COX-2, is believed to be a critical enzyme in the...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Vijitruth, Rattanavijit, Liu, Mei, Choi, Dong-Young, Nguyen, Xuan V, Hunter, Randy L, Bing, Guoying
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2006
נושאים:
Research
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440849/
https://ncbi.nlm.nih.gov/pubmed/16566823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-3-6
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