Pattern of dopaminergic loss in the striatum of humans with MPTP induced parkinsonism

OBJECTIVES—To examine the distribution of striatal dopaminergic function in humans with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to determine if there is a caudate-putamen gradient as is seen in idiopathic Parkinson's disease.
METHODS—We scanned nine humans ex...

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Bibliographic Details
Main Authors: Snow, B., Vingerhoets, F., Langston, J, Tetrud, J., Sossi, V., Calne, D.
Format: Artigo
Language:Inglês
Published: BMJ Group 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1736814/
https://ncbi.nlm.nih.gov/pubmed/10675212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.68.3.313
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