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Dopaminergic Denervation and Spine Loss in the Striatum of MPTP-treated Monkeys
Striatal spine loss is a key pathological feature of human Parkinson’s disease (PD) that can be induced after complete degeneration of the nigrostriatal dopaminergic system in rodent models of parkinsonism. In line with these observations, our findings reveal a significant (30–50%) reduction in spin...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680135/ https://ncbi.nlm.nih.gov/pubmed/18977221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2008.09.025 |
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