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Adaptive Evolution and Antiviral Activity of the Conserved Mammalian Cytidine Deaminase APOBEC3H

The APOBEC3 genes encode cytidine deaminases that act as components of an intrinsic immune defense that have potent activity against a variety of retroelements. This family of genes has undergone a rapid expansion from one or two genes in nonprimate mammals to at least seven members in primates. Her...

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Bibliografiske detaljer
Main Authors: OhAinle, Molly, Kerns, Julie A., Malik, Harmit S., Emerman, Michael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440450/
https://ncbi.nlm.nih.gov/pubmed/16571802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.8.3853-3862.2006
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