Juxtamembranous aspartic acid in Insig-1 and Insig-2 is required for cholesterol homeostasis

Insig-1 and Insig-2 are closely related proteins of the endoplasmic reticulum (ER) that mediate feedback control of cholesterol synthesis by sterol-dependent binding to the following two membrane proteins: the escort protein Scap, thus preventing proteolytic processing of sterol regulatory element-b...

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Detaylı Bibliyografya
Asıl Yazarlar: Gong, Yi, Lee, Joon No, Brown, Michael S., Goldstein, Joseph L., Ye, Jin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2006
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1435366/
https://ncbi.nlm.nih.gov/pubmed/16606821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601923103
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